{"id":10767,"date":"2020-07-05T15:33:32","date_gmt":"2020-07-05T12:33:32","guid":{"rendered":"http:\/\/katsanas.com\/?p=1514"},"modified":"2023-10-10T21:48:28","modified_gmt":"2023-10-10T21:48:28","slug":"antibakteriyel-cerrahi-ipliklerde-yuksek-verimli-kaplama-maddesi-klorheksidin","status":"publish","type":"post","link":"https:\/\/www.katsanas.com\/en\/antibakteriyel-cerrahi-ipliklerde-yuksek-verimli-kaplama-maddesi-klorheksidin\/","title":{"rendered":"ANT\u0130BAKTER\u0130YEL CERRAH\u0130 \u0130PL\u0130KLERDE Y\u00dcKSEK VER\u0130ML\u0130 KAPLAMA MADDES\u0130: KLORHEKS\u0130D\u0130N"},"content":{"rendered":"

\"\"<\/p>\n

ANT\u0130BAKTER\u0130YEL CERRAH\u0130 \u0130PL\u0130KLERDE Y\u00dcKSEK VER\u0130ML\u0130 KAPLAMA MADDES\u0130: KLORHEKS\u0130D\u0130N<\/h1>\n

S\u00fct\u00fcrler, bakterilerin yay\u0131ld\u0131\u011f\u0131 yaralardaki kapiler etkilere ba\u011fl\u0131 olarak zorlu cerrahi alan enfeksiyonlar\u0131na neden olabilir. Antibakteriyel s\u00fct\u00fcrler, bu komplikasyonlar\u0131, bakteriyel patojeni inhibe ederek \u00f6nleyebilir. Son zamanlarda; ilk olarak, triklosan direnci bildirilmi\u015ftir ve sonras\u0131nda alternatif maddeler klinik a\u00e7\u0131dan uygulanabilir bulunmu\u015ftur. Klorheksidin kimyasal ajan\u0131 da bu do\u011frultuda kullan\u0131lmaya ba\u015flanm\u0131\u015ft\u0131r.<\/p>\n

\u0130lk fizibilite \u00e7al\u0131\u015fmalar\u0131nda, klorheksidin kapl\u0131 s\u00fct\u00fcrlerin S. aureus\u2019a kar\u015f\u0131 y\u00fcksek etkinlik g\u00f6sterdi\u011fi g\u00f6sterilmi\u015ftir. Antibakteriyel s\u00fct\u00fcrler, inhibisyon bakterileri ile \u00e7evredeki \u00f6karyotik doku h\u00fccreleri aras\u0131ndaki biyolojik uyumlulu\u011fun s\u00fcrd\u00fcr\u00fclmesinde dengeyi sa\u011flamal\u0131d\u0131r. Agar plak dif\u00fczyon testlerinde, implanta ba\u011fl\u0131 enfeksiyonlar\u0131n ana patojeni Staphylococcus aureus kullan\u0131larak antibakteriyel etkinlik saptanm\u0131\u015ft\u0131r.<\/p>\n

Klorheksidin kaplamal\u0131 tekli cerrahi s\u00fct\u00fcrlerin mukavemet de\u011feri (n = 5), Avrupa Farmakopesine g\u00f6re (USP 1 s\u00fct\u00fcrler i\u00e7in gerekli minimum 50.8 N) belirlenmi\u015ftir. Test edilen t\u00fcm s\u00fct\u00fcrlerin mukavemeti de\u011ferleri, EP standard\u0131ndan daha y\u00fcksek ortalama maksimum mukavemet de\u011ferlerine sahip oldu\u011funu kan\u0131tlam\u0131\u015ft\u0131r.<\/p>\n

Ameliyatta cerrahi alan infeksiyonu halen \u00f6nemli bir komplikasyon olu\u015fturmaktad\u0131r. S\u00fct\u00fcrler, yap\u0131\u015fan patojenlerin \u00e7o\u011falmas\u0131yla ind\u00fcklenen, s\u00fct\u00fcrle ba\u011flant\u0131l\u0131 enfeksiyonlara neden olabilir. Yap\u0131\u015fkan bakteri, k\u0131lcal damar hareketiyle yaralara girer ve biyofilmler olu\u015fturarak kronik enfeksiyonlara neden olur. Cerrahi diki\u015fler i\u00e7in antibakteriyel kaplamalar, bakteri geli\u015fimini inhibe ederek s\u00fct\u00fcrlerin korunmas\u0131 yoluyla bu sorunu \u00e7\u00f6zebilir ve \u00f6nemli \u00f6l\u00e7\u00fcde maddi tasarruf da sa\u011flanabilir. Bu do\u011frultuda \u00f6nemli olan, \u00f6karyotik h\u00fccreler a\u00e7\u0131s\u0131ndan biyouyumlu olan, bakterilere kar\u015f\u0131 etkili koruma sa\u011flayan antibakteriyel s\u00fct\u00fcrlerin yayg\u0131nla\u015fmas\u0131d\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

S\u00fct\u00fcrler, bakterilerin yay\u0131ld\u0131\u011f\u0131 yaralardaki kapiler etkilere ba\u011fl\u0131 olarak zorlu cerrahi alan enfeksiyonlar\u0131na…<\/p>\n","protected":false},"author":2,"featured_media":10723,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"tags":[],"class_list":["post-10767","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-tr"],"_links":{"self":[{"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/posts\/10767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/comments?post=10767"}],"version-history":[{"count":1,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/posts\/10767\/revisions"}],"predecessor-version":[{"id":11123,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/posts\/10767\/revisions\/11123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/media\/10723"}],"wp:attachment":[{"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/media?parent=10767"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/categories?post=10767"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.katsanas.com\/en\/wp-json\/wp\/v2\/tags?post=10767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}